Broccoli compound helps type 2 diabetes mellitus
A report by Z. Bahadoran of Obesity Research Centers, Research Institute for Endocrine Sciences and…
A report by 
Z. Bahadoran of Obesity Research Centers, Research Institute for Endocrine Sciences and colleagues suggests that eating young broccoli sprouts or taking a nutritional supplement with a broccoli compound called sulforaphane may help treat type 2 diabetes mellitus.
Some functional foods and nutraceuticals are now used as nutritional supplements to treat or prevent type 2 diabetes or its long-term complications. Y oung broccoli sprouts contain many bioactive compounds such as sulforaphane which prior research has suggested may help type 2 diabetes mellitus.
The broccoli compound sulforaphane in hyperglycemic and oxidative conditions can "activate the NF-E2- related factor-2 (Nrf2)-dependent antioxidant response-signaling pathway, induces phase 2 enzymes, attenuates oxidative stress, and inactivates nuclear factor kappa-B (NF-κB), a key modulator of inflammatory pathways," the authors state in their report published in Journal of medicinal Food.
Importantly as the authors state, "sulforaphane induces some peroxisome proliferator-activated receptors, which contribute to lipid metabolism and glucose homeostasis."
It has been observed that type 2 diabetics eating broccoli sprouts with high sulforaphane had increased total antioxidant capacity in the blood and decreased oxidative stress, "lipid peroxidation, serum triglycerides, oxidized low-density lipoprotein (LDL)/LDL-cholesterol ratio, serum insulin, insulin resistance, and serum high-sensitive C-reactive protein."
Also evidence suggests sulforaphane may prevent nephropathy, fibrosis, and vascular complications associated with type 2 diabetes mellitus.
The authors concluded that sulforaphane and potentially other biotacive compounds found in young broccoli sprouts can be used as a dietary supplementary to treat type 2 diabetes.
In addition to the protective effect against type 2 diabetes mellitus, animal and in vitro studies show sulforaphane also has an antihypertensive, anticancer, antibacterial,cardioprotective, and hypocholesterolemic properties.
Z. Bahadoran of Obesity Research Centers, Research Institute for Endocrine Sciences and colleagues suggests that eating young broccoli sprouts or taking a nutritional supplement with a broccoli compound called sulforaphane may help treat type 2 diabetes mellitus.Some functional foods and nutraceuticals are now used as nutritional supplements to treat or prevent type 2 diabetes or its long-term complications. Y oung broccoli sprouts contain many bioactive compounds such as sulforaphane which prior research has suggested may help type 2 diabetes mellitus.
The broccoli compound sulforaphane in hyperglycemic and oxidative conditions can "activate the NF-E2- related factor-2 (Nrf2)-dependent antioxidant response-signaling pathway, induces phase 2 enzymes, attenuates oxidative stress, and inactivates nuclear factor kappa-B (NF-κB), a key modulator of inflammatory pathways," the authors state in their report published in Journal of medicinal Food.
Importantly as the authors state, "sulforaphane induces some peroxisome proliferator-activated receptors, which contribute to lipid metabolism and glucose homeostasis."
It has been observed that type 2 diabetics eating broccoli sprouts with high sulforaphane had increased total antioxidant capacity in the blood and decreased oxidative stress, "lipid peroxidation, serum triglycerides, oxidized low-density lipoprotein (LDL)/LDL-cholesterol ratio, serum insulin, insulin resistance, and serum high-sensitive C-reactive protein."
Also evidence suggests sulforaphane may prevent nephropathy, fibrosis, and vascular complications associated with type 2 diabetes mellitus.
The authors concluded that sulforaphane and potentially other biotacive compounds found in young broccoli sprouts can be used as a dietary supplementary to treat type 2 diabetes.
In addition to the protective effect against type 2 diabetes mellitus, animal and in vitro studies show sulforaphane also has an antihypertensive, anticancer, antibacterial,cardioprotective, and hypocholesterolemic properties.
